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Immune Tolerance and Tumor Immunology

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Air date: Wednesday, February 25, 2015, 4:15:00 PM
Time displayed is Eastern Time, Washington DC Local
Views: Total views: 433 (23 Live, 410 On-demand)
Category: Immunology
Runtime: 01:01:46
Description: The Immunology Interest Group

Chen Dong studies the regulation of immune system with a focus on T cell tolerance and helper T cell differentiation. After receiving his Ph.D. from the University of Alabama at Birmingham with Max Cooper and completing a postdoctoral fellowship at Yale University with Richard Flavell, Chen joined the faculty at University of Washington School of Medicine in 2000. In 2004 he moved to the Department of Immunology, University of Texas M.D. Anderson Cancer Center as an Associate Professor, becoming a Professor in 2008. In 2013, Chen moved to Beijing to build and lead the new Institute for Immunology at Tsinghua University. Among his many important contributions to immunology, Chen identified the TH17 cell lineage and elucidated their unique developmental regulation and critical function in inflammatory diseases. He has recently analyzed the differentiation of T follicular helper (Tfh) and regulatory (Tfr) cells and shown essential transcription factors in this process. He has also studied the roles of IL-17 family cytokines in inflammation and cancer and the underlying signaling mechanisms. In addition, he has identified and characterized important cell-surface and intracellular molecules involved in regulation of T cell activation and tolerance and has used genetic approaches to investigate the roles of various molecules in MAP kinase and ubiquitin/ubiquitin-like signaling pathways in the immune system.

For more information go to http://sigs.nih.gov/immunology/Pages/default.aspx
Author: Chen Dong, Tsinghua University
CIT Live ID: 15834
Permanent link: https://videocast.nih.gov/watch=15834

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