NIH VideoCast - Demystifying Medicine — Multiple Myeloma

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Demystifying Medicine — Multiple Myeloma

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Air date:	Tuesday, April 16, 2024, 4:00:00 PM Time displayed is Eastern Time, Washington DC Local
Views:	Total views: 268 (130 Live, 138 On-demand)
Category:	Demystifying Medicine
Runtime:	02:04:59
Closed captioning:	Check box to display CC outside of the video Note: You can drag the captioning window around and resize it
Description:	Although hope is on the horizon, multiple myeloma can bring a grim prognosis, a five-year survival rate of only about 60% in the United States, according to NCI data. This, however, is a stark improvement over the prognosis just a decade ago. The dozens of new treatments include multidrug cocktails and promising advances with Venetoclax therapy and CAR-T therapy, the latter two now in clinical trials. Our first speaker, Dr. Anderson, is the Kraft Family Professor of Medicine at Harvard Medical School and director of the LeBow Institute for Myeloma Therapeutics and Jerome Lipper Multiple Myeloma Center at Dana-Farber. His team has developed laboratory and animal models that have allowed for both identification of novel targets and validation of novel targeted therapies, and they have rapidly translated these studies "bench to bedside," culminating in FDA approval of novel targeted and immune therapies. This, in turn, has led to markedly improved patient outcomes. Our second speaker, Dr. Young, is a Stadtman Investigator on the NCI Lymphoid Malignancies Branch. His research program utilizes cutting-edge proteogenomic techniques, high-resolution microscopy imaging, and biochemical approaches to discover molecular mechanisms of pathogenic signaling in multiple myeloma with the goal of finding new opportunities for its targeted treatment. What progress has been made in extending life after a multiple myeloma diagnosis, and what are the stumbling blocks that make a cure so elusive? These are some of the discussion points for the next Demystifying Medicine. The Demystifying Medicine Series, jointly sponsored by FAES and NIH, includes presentations on pathology, diagnosis, and therapy in the context of major disease problems and current research. Primarily directed toward PhD students, clinicians and program managers, this series is designed to help bridge the gap between advances in biology and their application to major human diseases. Each session includes clinical and basic science components presented by NIH staff and invitees. All students, trainees, fellows, and staff are welcome to participate. For more information go to https://demystifyingmedicine.od.nih.gov

Author:	Kenneth Anderson (Dana Farber Cancer Institute/Harvard Medical School) and Ryan Young (NCI/CCR)

CIT Live ID:	54043
Permanent link:	https://videocast.nih.gov/watch=54043

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