NIH VideoCast - NIH Director's Seminar Series - Phthalate exposure and preterm birth: Findings from a pooled study of 16 US cohorts

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NIH Director's Seminar Series - Phthalate exposure and preterm birth: Findings from a pooled study of 16 US cohorts

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Air date:	Friday, February 9, 2024, 12:00:00 PM Time displayed is Eastern Time, Washington DC Local
Views:	Total views: 146 (97 Live, 49 On-demand)
Category:	NIH Director's Seminars
Runtime:	01:01:16
Closed captioning:	Check box to display CC outside of the video Note: You can drag the captioning window around and resize it
Description:	Phthalates diesters are found ubiquitously in personal care products and plastics, and human exposure is widespread. Exposure in pregnancy is of particular concern due to the endocrine activity and suspected reproductive toxicity of these compounds. The Pooled Phthalate and Preterm Birth Study is a collaboration between 16 US cohorts established to better understand the relationship between exposure to phthalates in pregnancy and preterm birth. Under this study, we investigated three aims. First, we examined the association between prenatal phthalate exposure and preterm birth, as well as the potential benefits of hypothetical interventions to reduce exposures during gestation. Second, we investigated the critical role that racial and ethnic disparities in phthalate exposure may play in these associations. Finally, we examined periods of susceptibility to exposure across the dynamic course of pregnancy.

NLM Title:	Phthalate exposure and preterm birth : findings from a pooled study of 16 US cohorts / Kelly Ferguson
Author:	Ferguson, Kelly. National Institutes of Health (U.S.),
Publisher:
Abstract:	(CIT): Phthalates diesters are found ubiquitously in personal care products and plastics, and human exposure is widespread. Exposure in pregnancy is of particular concern due to the endocrine activity and suspected reproductive toxicity of these compounds. The Pooled Phthalate and Preterm Birth Study is a collaboration between 16 US cohorts established to better understand the relationship between exposure to phthalates in pregnancy and preterm birth. Under this study, we investigated three aims. First, we examined the association between prenatal phthalate exposure and preterm birth, as well as the potential benefits of hypothetical interventions to reduce exposures during gestation. Second, we investigated the critical role that racial and ethnic disparities in phthalate exposure may play in these associations. Finally, we examined periods of susceptibility to exposure across the dynamic course of pregnancy.
Subjects:	Cohort Studies Dibutyl Phthalate--toxicity Environmental Exposure--adverse effects Infant, Premature Maternal-Fetal Exchange--physiology Premature Birth--chemically induced
Publication Types:	Lecture Webcast

NLM Classification:	WS 410
NLM ID:	9918820069406676
CIT Live ID:	54223
Permanent link:	https://videocast.nih.gov/watch=54223

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