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Genomics of Tolerance
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Air date:
Wednesday, November 19, 2008,
4:15:00 PM Time displayed is Eastern Time, Washington DC Local
Views:
Total views: 133 * This only includes stats from October 2011 and forward.
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Description:
Christophe has a long time interest in the study of thymic tolerance and development of organ specific autoimmunity. During a long-standing collaboration with Diane Mathis, he has studied animal models for diabetes, arthritis and Aire deficiencies. His current research applies a wide range of technologies to study tolerance mechanisms, including mouse genetics, gene expression profiling, mass spectrometry, RNAi screens and imaging tools to track autoimmune inflammation in vivo. He is currently studying how FoxP3 coordinates with other elements in specifying the different facets of the Treg phenotype. His seminar will surely be of interest to many members of the NIH immunology community.